Sory to hear that, they say my baby has a poly A gene mutation so they would expect for him to have a mild case of sickle beta plus thal, he has been prescribed pennicillin for life, but I have not started to give him this yet, I think it is better to wait until his fetal hemaglobin has gone, were u prescribed this? What kinda symptoms does ur sister get? Does she have many crisis? How regular are yours? I hope u donmind me asking all these questions, I am so confused and worried about my sons condition, hope to hear from u soon x